Medicinal sciences
Seyed Hossein Shahcheraghi; Venant Tchokonte-Nana; Jamshid Ayatollahi; Marzieh Lotfi; Mahdie Hamidfar; Benjamin Longo-Mbenza
Abstract
Coronavirus is a non-segmented virus related to Coronaviridae family with an envelope and RNA that has a huge positive-sense single-stranded genome. The causative agent of COVID-19, severe acute respiratory coronavirus syndrome-2 (SARS-CoV-2) first appeared in China in 2019. The role of these viruses ...
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Coronavirus is a non-segmented virus related to Coronaviridae family with an envelope and RNA that has a huge positive-sense single-stranded genome. The causative agent of COVID-19, severe acute respiratory coronavirus syndrome-2 (SARS-CoV-2) first appeared in China in 2019. The role of these viruses in pneumonia has greatly improved through molecular techniques. The virus structural proteins, viral replication factors, viral endocytosis process and enzymes are the key targets for designing drugs against COVID-19. This review considered the main molecular and cellular targets as well as peptide-based and pharmaceutical treatments for COVID-19 aiming for a better design of drugs against viruses with the best insights on key factors in this infection.
Medicinal sciences
Jamshid Ayatollahi; Forouzan Desin; Mohammad Sharifyazdi; Seyed Alireza Mousavi; Zohre Akhondimeybodi; Faezehsadat Heidari; Samaneh Mazidi; Vahid Sharifi; Sadiah Dehghani; Alireza Etemadieh; Mahdie Hamidfar; Seyed Hossein shahcheraghi
Abstract
Various factors are effective in reduction or increase of Erythrocyte Sedimentation Rate (ESR). This study was designed to investigate the effective factors on ESR in adults participating study in Yazd in Iran. In this study, the data in cohort study was used. The variables of age, sex, Body Mass Index ...
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Various factors are effective in reduction or increase of Erythrocyte Sedimentation Rate (ESR). This study was designed to investigate the effective factors on ESR in adults participating study in Yazd in Iran. In this study, the data in cohort study was used. The variables of age, sex, Body Mass Index (BMI), alcohol consumption, smoking, infection, inflammation, cancer, and blood pressure were collected. There is a significant relationship between age, sex, systolic blood pressure, BMI, physical activity, joint and heart pain, osteoporosis and smoking history with ESR. Cancer history and diastolic blood pressure variables have no significant effect on ESR values. Results showed that ESR levels in an adult population are generally affected by age and sex.
